J'sphere H80

J'sphere ODS-H80 Guard Columns from YMC Europe GMBH

YMC recommends that you always use a guard column with the same packing material and of the recommended inner diameter for your column. A YMC guard column is normally composed of a cartridge holder and a guard cartridge. The holder can be used repeatedly. Guard cartridges should be changed frequently in order to maximise their protection of the main column.

Alkyl chains of various length, such as C18, C8 and C4, are commonly used for bonding during the synthesis of reversed phase materials to provide different polarity. YMC however, have applied another approach for creating a range of divergent polarities and improving the consistency in the synthesis of reversed phase packings. YMC kept the C18-alkyl chain length constant, but specifically changed content of C18 groups at the silica surface, to produce three different J´sphere ODS packings with graduated hydrophobicity.

J'sphere ODS-H80 is the most hydrophobic stationary phase in the J'sphere series. It is densely covered with polymeric bonded C18 groups yielding a high carbon content and providing a strong, dominant, lipophilic interaction with the nonpolar sites of the sample molecules. However, the ability to form H-bonding gives additional selectivity, which is essential for difficult separations, such as drug and corresponding metabolite discrimination. Even stereoisomers can be separated by J'sphere ODS-H80 columns.